Publications

Claudia Fruijtier-Pölloth

Claudia Fruijtier-Pölloth is the author of more than 400 quality-reviewed internal toxicology study reports and author of several publications:

• Chadhuri, I., Fruijtier-Poelloth, C., Ngiewih, Y., Levy, L. (2018). Evaluating the evidence on genotoxicity and reproductive toxicity of carbon black: a critical review. Critical Reviews in Toxicology 48(2), 143-169.

• Chaudhuri, I., Fruijtier-Pölloth, C., Ngiewih, Y., & Levy, L. (2017). Evaluating the evidence on genotoxicity and reproductive toxicity of carbon black: a critical review. Critical Reviews in Toxicology, 48(2), 143–169. https://doi.org/10.1080/10408444.2017.1391746 

• Fruijtier-Pölloth, C. (2016). The safety of nanostructured synthetic amorphous silica (SAS) as a food additive (E 551). Arch Toxicol. doi:10.1007/s00204-016-1850-4.

• Fruijtier-Pölloth, C. (2012). The toxicological mode of action and the safety of synthetic amorphous silica - A nanostructured material. Review Article. Toxicology 294, Issues 2-3, 61- 79.

• Carmichael, N., Bausen, M., Boobis, A., Cohen, S., Embry, M., Fruijtier-Pölloth, C., Greim, H., Lewis, R., Meek, M., Mellor, H., Vickers, C., Doe, J. (2011). Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview. Critical Reviews in Toxicology 41(3), 175-186.

• Fruijtier-Pölloth, C. (2009). Alkyl sulfates, alkane sulphanates, and alpha-olefin sulphonates. Toxicology Letters 189, Supplement 1, S4-S5, Abstracts of the 46th Congress of the European Societies of Toxicology.

• Fruijtier-Pölloth, C. (2009). The safety of synthetic zeolites used in detergents. Arch Toxicol. 83(1), 23-25.

• Fruijtier-Pölloth, C. (2007). Book review: Nanofabrication towards Biomedical Applications. Regulatory Affairs Focus, July 2007, p. 7-8.

• Fruijtier-Pölloth, C. (2005). Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products. Review Article. Toxicology 214, Issues 1-2, 1-38.

• Fox, K.K., Cassani, G., Facchi, A., Schroeder, F.R., Pölloth, C., Holt, M.R. (2002). Measured variations in boron loads reaching European sewage treatment plants. Chemosphere 47, 499-505.

• Bishop, W.E. and Pölloth, C. (2000). The Alliance for Chemical Awareness (ACA) and the Human and Environmental Risk Assessment (HERA) Project: Risk Assessment and Communication Programs for High Production Volume Chemicals (HPVs). Meeting Paper, Society for Risk Analysis 2000 Annual Meeting.

• Scailteur, V., Pölloth, C., Jassogne, Ch. (2000). HERA – Human and Environmental Risk Assessment Industry Initiative for Chemicals used in Household Detergent and Cleaning Products. SÖFW Journal, 126(5), 13-15.

• Basketter, D., Hamaide, N., Lichtfus, G., Pölloth, C., Wiebel, F. (2000). European Labelling Requirements for Skin Sensitisers. European Society of Contact Dermatitis, Amsterdam 2000.

• Pölloth, C. (2000). Views and Perspectives on Risk Assessment of Detergents and Cleaning Products. Jorn. Com. Esp. Deterg. 30, Annex, p. 39-46.

• Pölloth, C. et al. (2000). International Multi-Laboratory Validation Study of an Organotypic Skin Culture as a Preclinical Screen for Cumulative Irritation of Surfactants. In vitro and Molecular Toxicology.

• Pölloth, C. and Mangelsdorf, I. (1997). Commentary on the Application of (Q)SARs to the Toxicological Evaluation of Existing Chemicals. Chemosphere 35/11, p. 2525-2542.

• Pölloth, C., Remmele, M., Deckardt, K., Schulte, S. (1996). New Screening Methods in Toxicology: in vitro Tests for Skin and Eye Irritation and Dermal Penetration. BASF AG, Ludwigshafen/Germany.

• Jäckh, R., Pölloth, C., and Deckardt, K. (1996). Cytotoxicity Screening: Extracellular Lactate Levels as an Indicator of Functional Toxicity. Abstracts of the German Society of Pharmacology and Toxicology, 1996.

• Bahnemann, R., Pölloth, C., Küttler, K., Gans, G., Mellert, W., Kaufmann, W. (1995). S-phase Response (BrdU-Immunohistochemistry), an Important Tool in the Evaluation of a Nongenotoxic Carcinogen. Abstract. 2nd International Conference - Carcinogenesis - New Methods, Interpretation - Risk Assessment. Tours, April 1995.

• Pölloth, C. (1994). Chapter "Toxicology" in "Ethylacrylat", BUA Report, VCH Weinheim.

• Pölloth, C. (1994). Chapter "Toxicology" in "Butylacrylat", BUA Report, VCH Weinheim.

• Mellert, W., Pölloth, C., Deckardt, K., Gembardt, Ch., Kaufmann, W. (1994). Effects of N-Allylpyridiniumchloride in vivo and Binding to Cholinergic Receptor Subtypes in vitro. German Society of Pharmacology and Toxicology.

• Pölloth, C., Jäckh, R., Sauter, H., Roehl, R. (1992). Cytotoxicity Screening in Mammalian Cell Cultures. BASF AG, Ludwigshafen/Germany.

• Pölloth, C. (1989). Spectroscopy Studies in Crown Ether Host-Guest Complexes. University of Ulm/Germany.

• Pölloth, C. (1988). The Isoelastic Hip Endoprosthesis. Thesis. University of Ulm/Germany.

Adriaan Fruijtier

• Phillips, R., Fruijtier, A., and Placchi, M. (2016). Can Health Technology Assessment be Used to Demonstrate Significant Benefits for an Orphan Medicinal Product in the EU? Regulatory Focus. July 2016. RAPS.

• Fruijtier, A. (2011). Registration Procedures for Medicinal Products: Update of Chapter 15 in Fundamentals of EU Regulatory Affairs, Fifth Edition, RAPS, 141-153.

• Fruijtier, A. (2008). Pharmaceutical Postmarketing and Compliance with the Marketing Authorisation. Update of Chapter 13 in Michor, S., Müller, LJ. (eds). 2008 Fundamentals of EU Regulatory Affairs, RAPS, 147-156.

• Fruijtier, A. (2008). Registration Procedures for Medicinal Products: Past, Present, and Future. Update of Chapter 12 in Michor, S., Müller, LJ. (eds). 2008 Fundamentals of EU Regulatory Affairs, RAPS, 133-146.

• Fruijtier, A. (2008). Overview of Authorisation Procedures for Medicinal Products. Update of Chapter 2 in Michor, S., Müller, LJ. (eds), 2008 Fundamentals of EU Regulatory Affairs, RAPS, 15-26.

• Fruijtier, A. (2007). EMEA/CHMP Think-Tank Group Report on Innovative Drug Development. Regulatory Affairs Focus, October 2007, 15-18.

• Fruijtier, A. (2006). Pharmaceutical Postmarketing and Compliance with the Marketing Authorisation. Update of Chapter 12 in Michor, S., Rowland, K. (eds). 2006 Fundamentals of EU Regulatory Affairs, RAPS, 137-144.

• Fruijtier, A. (2006). Registration Procedures for Medicinal Products: Past, Present, and Future. Update of Chapter 11 in Michor, S., Rowland, K. (eds). 2006 Fundamentals of EU Regulatory Affairs, RAPS, 125-136.

• Fruijtier, A. (2006). Overview of Authorisation Procedures for Medicinal Products and Medical Devices. Update of Chapter 2 in Michor, S., Rowland, K. (eds). 2006 Fundamentals of EU Regulatory Affairs, RAPS, 11-28.

• Fruijtier, A. (2001). Submissions of electronic Marketing Authorisations (eMAA) in the EU.Good Clinical Practice Journal, Volume 8, No.11.

• Lindelauf, F., Fruijtier, A. (1995). Gele verkleuring dihydralazine-infusievloeistof door PVC. Ziekenhuisfarmacie 11:139.

• Fruijtier, A., Lingeman, H., Beijnen, J. (1990). Derivatization Reactions and Kinetics in Liquid Chromatography. In Lingeman, H., Underberg W., red. Detection-Oriented Derivatization Techniques in Liquid Chromatography.New York, Marcel Dekker, Inc, 51-85.

• Stolk, L., Fruijtier, A., Wiltink, E. (1986). Stabiliteit retentieklysma met 5-aminosalicylzuur/sulfaguanidine/prednisolonfosfaat. Pharm Weekbl 121:821-2.

• Stolk, L., Fruijtier, A., Umans, R. (1986). Vincristine oplossing (1 mg/ml) voor injectie in plastic wegwerpspuitjes: stabiliteit na invriezen bij -20 ºC. Ziekenhuisfarmacie 2:136-7.

• Stolk, L., Fruijtier, A., Umans, R (1986). Stability after freezing and thawing of solutions of mitomycin C in plastic minibags for intravesical use. Pharm Weekbl (Sci) 8:286-8.